Table 2.
Summary of clinical and MRI variables and association with surgical margin status.
| Surgical margin |
||||
|---|---|---|---|---|
| Total (n = 41) | Negative (n = 24) | Close (n = 15), Positive (n = 2) | ||
| Patient's baseline characteristics | p value | |||
| Age (years) | 51 [14] (35–74) | 51 [10] (40–74) | 47 [13.8] (35–72) | 0.307a |
| BMI (kg/m²) | 21.9[5.4] (16.8–34.9) | 21.3 [5.0] (17.6–28.9) | 22.7[6.0] (16.8–34.9) | 0.751a |
| Pathological findings | ||||
| Direction of shortest lateral margin | ||||
| From the nipple to cancer | 16 (39) | |||
| Perpendicular to above | 25 (61) | |||
| NMC diameter in the shortest lateral margin (mm) | 23 [28.5] (3–135) | 18 [14.5] (3–75) | 38 [28.55] (10–135) | |
| Maximum diameter of NMC (mm) | 30 [34.3] (3–135) | 20.5 [19.0] (7−75) | 50 [26.8] (13–135) | 0.002*,a |
| Width of safety margin (mm) | 0.105b | |||
| 10 mm | 7 (17.1) | 2 | 5 | |
| 15 mm | 34(82.9) | 22 | 12 | |
| Imaging variables on MRI | ||||
| BPE on prone MRI | 0.812b | |||
| Minimal/Mild | 25 (61) | 15 | 10 | |
| Moderate/Marked | 16 (39) | 9 | 7 | |
| BPE on supine MRI | 0.507b | |||
| Minimal/Mild | 29 (70.7) | 18 | 11 | |
| Moderate/Marked | 12 (29.3) | 6 | 6 | |
| NME diameter in the shortest lateral margin (mm) | 20 [17.8] (0–80) | 14.5[13.0] (0–80) | 23 [24.5] (0–80) | |
| Maximum diameter of NME (mm) | 27 [21.0] (0–80) | 21.5[19.8] (0–80) | 30 [28.3] (0–80) | 0.028*,a |
| Discrepancy of the diameters between NMC and NME (mm) | 6 [14.5] (−24–55) | 0.5 [12.3] (−24–32) | 10 [16.3] (−7–55) | 0.010*,a |
Median [IQR]
Negative; > 2 mm; Close: = or < 2 mm; Positive: no tumor on ink
NMC, nonmass component shown by pathology; NME, nonmass enhancement shown by supine MRI
a
Mann-Whitney U test
b
Fisher’s Exact Test
*
p < 0.05