Figure 6. Glial cell distribution track with age-related NODDI diffusion measures.
Spatial distribution of glial cell associations with white matter (left panel) and corresponding age associations (right panel) across whole brain white matter tracts for NODDI diffusion estimates (i.e., ISOVF=isotropic volume fraction; OD=orientation dispersion; ICVF=intracellular volume fraction). Scatter plots colored by the respective diffusivity measure show the positive relationship between age regressed NODDI diffusion estimates (b) and glial cell enrichment, such as astrocytes and microglia. Correlations were estimated by Spearman’s Rho.
