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Receiver operating characteristic (ROC) curves comparing the predictive performance of age-, sex-, and fasudil-treatment-adjusted models for distinguishing fast vs. slow progressors based on the decline of ALSFRS-R (A) and sVC (B). ROC curves, as well as AUC and 95% CI are displayed for NfL/MUNIX-10 ratio (purple), NfL only (teal), and MUNIX-10 only (yellow).
