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[Preprint]. 2025 Sep 4:2025.09.02.25334926. [Version 1] doi: 10.1101/2025.09.02.25334926

Table 2.

Standardized model results for effects of family history and covariates on latent mediators.

Predictors Mediators
Reward
β SE p-value
Family History 0.282 0.103 0.006
Sex −0.007 −0.167 0.868
Adolescent Binge
Drinking −0.053 0.079 0.504
Childhood Trauma 0.000 0.003 0.885
No Choice Variation 0.131 0.081 0.110
Cognitive Control
β SE p-value
Family History −0.086 0.098 0.382
Sex 0.027 0.083 0.747
Adolescent Binge
Drinking 0.013 0.074 0.857
Childhood Trauma 0.002 0.776 0.438
No Choice Variation −0.144 0.160 0.368
Prospection
β SE p-value
Family History −0.035 0.102 0.734
Sex 0.047 0.031 0.127
Adolescent Binge
Drinking −0.062 0.033 0.065
Childhood Trauma −0.004 0.001 0.010
No Choice Variation 0.040 0.057 0.486
Delay Discounting
β SE p-value
Family History −0.146 0.070 0.037
Sex 0.119 0.037 0.001
Adolescent Binge
Drinking −0.033 0.043 0.440
Childhood Trauma 0.001 0.002 0.550
No Choice Variation 0.403 0.037 0.000

Latent variable for reward was comprised of the bilateral nucleus accumbens, cognitive control was comprised of the bilateral caudal middle frontal gyrus, prospection was comprised of the bilateral hippocampus, and delay discounting was comprised of the area-under-the-curve behavior for $100 and $1000 options.