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. 2025 Aug 29;13:1617155. doi: 10.3389/fped.2025.1617155

Table 1.

The demographical and clinical characteristics of NE neonates (n = 138).

Infant characteristics at enrollment NE (n = 65) NE (n = 73)
No/mild injury on MRI Moderate/severe injury on MRI
Sex (%)
Female 46 40
Male 54 60
Gestational age in weeks (mean ± SD) 38 ± 2 38 ± 2
Birth weight in grams (mean ± SD) 3,219 ± 752 3,212 ± 740
Apgar score at 1 min (mean ± SD) 2 ± 2 2 ± 2
Apgar score at 5 min (mean ± SD) 4 ± 2 4 ± 2
Apgar score at 10 min (mean ± SD) 5 ± 3 5 ± 3
Sentinel event n (%) 28 (43%) 24 (33%)
C- section delivery n (%) 42 (65%) 41 (56%)
*Respiratory support n (%) 55 (85%) 70 (96%)
*Ventilator n (%) 44 (68%) 61 (84%)
CPAP n (%) 5 (8%) 8 (11%)
*Room Air n (%) 10 (15%) 3 (4%)
*Inototropic support n (%) 22 (34%) 44 (60%)
*History of seizures n (%) 9 (14%) 36 (49%)
SARNAT score II n (%) 31 (48%) 25 (34%)
*SARNAT score III n (%) 5 (8%) 27 (37%)
Umbilical cord arterial pH (mean ± SD) 6.96 ± 0.18 6.96 ± 0.18
Umbilical cord arterial deficit (mean ± SD) −15 ± 6 −16 ± 6
Initial pH (mean ± SD) 7.11 ± 0.17 7.11 ± 0.17
Initial base deficit (mean ± SD) −15 ± 6 −16 ± 6
Initial lactate (mean ± SD) 10 ± 5 11 ± 5
Time to MRI (median [IQR]) 4 [4–6] 4 [4–6]
Length of stay (median [IQR]) 15 [10–27] 15 [9–32]

NE, neonatal encephalopathy; SD, standard deviation; IQR, interquartile range * p < 0.05.