Table 2.
Restoration of spermatogenesis in SI/SId male mice after LV-CMV-KL2 injection
| Recipient SI/SId mouse no. | Days after operation | Uninjected left testis weight, mg | Injected right testis weight, mg | Weight change, % | Percent positive tubules stained with anti-calmegin antibody |
|---|---|---|---|---|---|
| 118 | 28 | 12 | 25 | 208 | 53.7 (65/121) |
| 119 | 28 | 10 | 21 | 210 | ND* |
| 115 | 56 | 10 | 30 | 300 | 58.1 (61/105) |
| 100 | 63 | 10 | 17 | 170 | 37.5 (60/160) |
| 204 | 85 | 11 | 27 | 245 | 42.5 (68/160) |
| 205 | 85 | 10 | 29 | 290 | 47.5 (57/120) |
| 99 | 107 | 12 | 32 | 267 | ND† |
| 116 | 142 | 11 | 22 | 200 | 51.6 (66/128) |
| 117 | 142 | 11 | 17 | 155 | 41.3 (43/104) |
| Average | 10.8 ± 0.8 | 24.4 ± 5.5 | 227 ± 51 | 47.5 ± 7.4 (420/898) |
*
Testes were subjected to Western blot analysis.
†
Testicular cells were collected and subjected to intracytoplasmic sperm injection.