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. 2025 Aug 29;14(17):1346. doi: 10.3390/cells14171346
BBB Blood–Brain Barrier
BRB Blood–Retinal Barrier
iBRB Inner Blood–Retinal Barrier
oBRB Outer Blood–Retinal Barrier
Cldn5 Claudin-5
TJs Tight Junctions
ECs Endothelial Cells
EVs Extracellular Vesicles
CNS Central Nervous System
ZO-1 Zonula Occludens-1
GDNF Glial Cell Line-Derived Neurotrophic Factor
MAPK Mitogen-Activated Protein Kinase
ERK Extracellular Signal-Regulated Kinase
PI3K Phosphoinositide 3-Kinase
Akt Protein Kinase B
FOXO1 Forkhead Box O1
MS Multiple Sclerosis
EAE Experimental Autoimmune Encephalomyelitis
CD Cluster of Differentiation (e.g., CD4+ T cells)
HG High Glucose
AGE Advanced Glycation End Products
TEER Transendothelial/Transepithelial Electrical Resistance
HIV Human Immunodeficiency Virus
OCD Obsessive–Compulsive Disorder
IL-6 Interleukin-6
IR Insulin Receptor
VEC Vascular Endothelial Cadherin
VDR Vitamin D Receptor
IBD Inflammatory Bowel Disease
PBS Phosphate-Buffered Saline
DKD Diabetic Kidney Disease
DN Diabetic Nephropathy
CKD Chronic Kidney Disease
cSCC Cutaneous Squamous Cell Carcinoma
EpV Epidermodysplasia Verruciformis
LPS Lipopolysaccharide
MMP3 Matrix Metalloproteinase 3
JAM-A Junctional Adhesion Molecule-A
VE-cadherin Vascular Endothelial Cadherin
SH-SY5Y Human Neuroblastoma Cell Line
U251 Human Glioblastoma Astrocytoma Cell Line
hCMEC/D3 Human Cerebral Microvascular Endothelial Cells (immortalized line)