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. 2025 Sep 4;17(17):2900. doi: 10.3390/cancers17172900
CiRT Checkpoint Inhibitor Response Test
CLIA Clinical Laboratory Improvement Amendments
CPT PLA Current Procedural Terminology Proprietary Laboratory Analyses Code
CR Complete Response
CTLA-4 Cytotoxic T-Lymphocyte Antigen 4
ECOG Eastern Cooperative Oncology Group
GCP Good Clinical Practice
HEOR Health Economic Outcomes Research
HPD Hyperprogressive Disease
HPRR High Probability of Response Result (CiRT classification)
ICI Immune Checkpoint Inhibitor
IrAE Immune-related Adverse Event
IRB Institutional Review Board
LPRR Low Probability of Response Result (CiRT classification)
MSI/MMR Microsatellite Instability/Mismatch Repair
OS Overall Survival
ORR Objective Response Rate
PD Progressive Disease
PD-1 Programmed Cell Death Protein 1
PD-L1 Programmed Death-Ligand 1
PFS Progression-Free Survival
PR Partial Response
RECIST Response Evaluation Criteria in Solid Tumors
SD Stable Disease
SDoH Social Determinants of Health
TKI Tyrosine Kinase Inhibitor
TMB Tumor Mutational Burden
uHCC Unresectable Hepatocellular Carcinoma (Advanced Liver Cancer)