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. 2025 Aug 27;26(17):8304. doi: 10.3390/ijms26178304
4-HNE 4-Hydroxynonenal
ACD Anemia of chronic disease
AI Anemia of inflammation
AKT/PKB Protein kinase B
ALAS2 5′-Aminolevulinate synthase 2
AMPK AMP-activated protein kinase
ASC Apoptosis-associated speck-like protein containing a CARD
ATMs Adipose tissue macrophages
ATP Adenosine triphosphate
BAT Brown adipose tissue
BMP6 Bone morphogenetic protein 6
BRINDA Biomarkers reflecting inflammation and nutritional determinants of anemia
C/EBP CCAAT/enhancer-binding protein
Ca2+ Calcium ion
CARD Caspase recruitment domain
CD11c+ Cluster of differentiation 11c positive
CD163 Cluster of differentiation 163
CD4+ T cells Cluster of differentiation 4 positive T lymphocytes
CHOP C/EBP homologous protein
Cl Chloride ion
CLS Crown-like structures
CODEX CO-Detection by indEXing
CREB cAMP response element-binding protein
DAMPs Damage-associated molecular patterns
Dcytb Duodenal cytochrome b
DFO Deferoxamine
DFP Deferiprone
DFX Deferasirox
DHA Docosahexaenoic acid
DIOS Dysmetabolic iron overload syndrome
DNA Deoxyribonucleic acid
DMT1 Divalent metal transporter 1
Fe–S Iron–sulfur cluster
Fe2+ Ferrous iron
Fe3+ Ferric iron
FBXL5 F-box and leucine-rich repeat protein 5
FOXO1 Forkhead box protein O1
FPN/Ferroportin Ferroportin (iron exporter), encoded by SLC40A1
GPX4 Glutathione peroxidase 4
GSDMD Gasdermin D
H2O2 Hydrogen peroxide
HAMP/HAMP1 Hepcidin antimicrobial peptide (gene)
HCD High-carbohydrate diet
HERC2 HECT and RLD domain-containing E3 ubiquitin protein ligase 2
HFD High-fat diet
HFE High Fe gene (homeostatic iron regulator)
HIF-2α Hypoxia-inducible factor 2 alpha
HIFs Hypoxia-inducible factors
HJV Hemojuvelin
HMGB1 High mobility group box 1
HO-1 Heme oxygenase-1
IAPP Islet amyloid polypeptide
IL-18 Interleukin-18
IL-1β Interleukin-1 beta
IL-1R Interleukin-1 receptor
IL-22 Interleukin-22
IL-6 Interleukin-6
iWAT Inguinal white adipose tissue (subcutaneous)
IRE/IREs Iron responsive element (s)
IRP/IRPs Iron regulatory protein (s)
IRS Insulin receptor substrate
IRS-1 Insulin receptor substrate 1
JAK–STAT3 Janus kinase–signal transducer and activator of transcription 3
JNK/MAPK c-Jun N-terminal kinase/mitogen-activated protein kinase
LIP Labile iron pool
LPS Lipopolysaccharide
LRR Leucine-rich repeat
MAPK Mitogen-activated protein kinase
MAVS Mitochondrial antiviral signaling protein
MFehi Macrophage ferritin-expressing high iron phenotype
MFelo Macrophage ferritin-expressing low iron phenotype
MIBI-TOF Multiplexed ion beam imaging by time-of-flight
MMe Metabolically activated macrophage phenotype
MRI Magnetic resonance imaging
mTOR Mammalian (mechanistic) target of rapamycin
mtROS Mitochondria-derived reactive oxygen species
Na+ Sodium ion
NCOA4 Nuclear receptor coactivator 4
NEK7 NIMA-related kinase 7
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NLRP3 NOD-, LRR-, and pyrin domain-containing protein 3
NRF2 Nuclear factor erythroid 2–related factor 2
NTBI Non–transferrin-bound iron
PAMPs Pathogen-associated molecular patterns
PUFAs Polyunsaturated fatty acids
RAGE Receptor for advanced glycation end products
ROS Reactive oxygen species
SAT Subcutaneous adipose tissue
sTfR Soluble transferrin receptor
SLC40A1 Solute carrier family 40 member 1 (gene encoding ferroportin)
SOCS Suppressor of cytokine signaling
T2D Type 2 diabetes mellitus
Tf/TfR/TfR1 Transferrin/Transferrin receptor/Transferrin receptor 1
THP-1 Human myelomonocytic cell line THP-1
TLR/TLR4 Toll-like receptor/Toll-like receptor 4
TNF-α Tumor necrosis factor alpha
TRX Thioredoxin
TXNIP Thioredoxin-interacting protein
UCP1 Uncoupling protein 1
UTR Untranslated region
VAT Visceral adipose tissue
vWAT Visceral white adipose tissue