CHOW	CHOW diet
HFD	High-fat diet
VAT	Visceral adipose tissue
VA	Visceral adipocyte
BAT	Brown adipose tissue
PAT	Perivascular adipose tissue
SAT	Subcutaneous adipose tissue
GAS	Gastrocnemius
OGTT	Oral glucose tolerance test (OGTT)
ITT	Insulin tolerance test
NTA	Nanoparticle tracking analysis
TEM	Transmission electron microscopy
HFD VA	High-fat diet visceral adipocyte
HFD VAD-ev	High-fat diet visceral adipocyte -derived extracellular vesicle
CO-HFD VA	C2C12 cells were seeded in the lower chamber of Transwell plates, while HFD VA cells were plated in the upper chamber
CO-GW4869	C2C12 cells were seeded in the lower chamber of Transwell plates, while HFD VA cells were plated in the upper chamber with GW4869
HFD+DMSO	HFD mice were intraperitoneally injected with DMSO
HFD+GW4869	HFD mice were intraperitoneally injected with GW4869
F4/80	Mouse egf-like module-containing mucin-like hormone receptor-like 1
CD11b	Cyclin-dependent kinase 11b
CD86	T-lymphocyte activation antigen CD86
CD206	Macrophage mannose receptor 1
MyoD	Myoblast determination protein
PAX7	Paired box protein PAX-7
MyoG	Myogenic
MYH3	Myosin heavy chain 3
FBXO32	Recombinant f-box protein 32
Trim63	Tripartite motif-containing protein 63
CCL2	C C motif ligand 2
IL-6	Interleukin 6
IL-1β	Interleukin 1β
iNOS	Nstitute nacional de obras sanitarias
TNFa	Tumor necrosis factor-a
M0+Ev-NC	RAW264.7 cells treated for 24 h with HFD VAD-evs loaded with the miR-155 inhibitor negative control.
M0+Ev-miR155 inhibitor	RAW264.7 cells treated for 24 h with HFD VAD-evs loaded with miR-155 inhibitor.
AAV-NC	AAV vector treatment was used as the negative control
HFD+AAV NC	AAV NC was injected intraperitoneally on the first day and via the tail vein on the third day, respectively (100 μL/day, start at 9 weeks of age).
HFD+AAV-155	AAV-155 was injected intraperitoneally on the first day and via the tail vein on the third day, respectively (100 μL/day, start at 9 weeks of age).
SFCM	SFCM was harvested from RAW264.7 cells treated for 24 h with HFD VAD-evs
SFCM NCev	SFCM was harvested from RAW264.7 cells treated for 24 h with HFD VAD-evs loaded with the miR-155 inhibitor negative control.
SFCM INev	SFCM was harvested from RAW264.7 cells treated for 24 h with HFD VAD-evs loaded with miR-155 inhibitor.