| ALS | amyotrophic lateral sclerosis |
| fALS | familial ALS |
| sALS | sporadic ALS |
| CNS | central nervous system |
| Tregs | regulatory T cells |
| DMM | disease-modifying molecule |
| BDNF | brain-derived neurotrophic factor |
| scFv | single-chain variable fragment |
| CAR | chimeric antigen receptor |
| SOD1 | superoxide dismutase-1 |
| hSOD1 | human SOD1 |
| NSG | NOD.Cg-Prkdc scid IL2rγ tm1Wjl |
| mSOD1-NSG | G93A hSOD1-NSG transgenic mice |
| NTLs | non-transgenic littermates |
| Luc-SH-SY5Y | luciferase-expressing SH-SY5Y cell line |
| IHC | immunohistochemistry |
| PBMCs | peripheral blood mononuclear cells |
| IP | intraperitoneal |
| IV | intravenous |