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. 2025 Aug 26;14(17):1318. doi: 10.3390/cells14171318
ALS amyotrophic lateral sclerosis
fALS familial ALS
sALS sporadic ALS
CNS central nervous system
Tregs regulatory T cells
DMM disease-modifying molecule
BDNF brain-derived neurotrophic factor
scFv single-chain variable fragment
CAR chimeric antigen receptor
SOD1 superoxide dismutase-1
hSOD1 human SOD1
NSG NOD.Cg-Prkdc scid IL2rγ tm1Wjl
mSOD1-NSG G93A hSOD1-NSG transgenic mice
NTLs non-transgenic littermates
Luc-SH-SY5Y luciferase-expressing SH-SY5Y cell line
IHC immunohistochemistry
PBMCs peripheral blood mononuclear cells
IP intraperitoneal
IV intravenous