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. 2025 Sep 3;17(17):2895. doi: 10.3390/cancers17172895
ACGM American College of Medical Genetics and Genomics
ALK Anaplastic lymphoma kinase
EGFR Epidermal growth factor receptor
FFPE Formalin-fixed, paraffin-embedded
HR Hazard ratio
ICI Immune-checkpoint inhibitor
IHC Immunohistochemistry
IL-1β Interleukin-1β
MMR Mismatch repair
MSI Microsatellite stability
NGS Next-generation sequencing
NSCLC Non-small cell lung cancer
OS Overall survival
PD-L1 Programmed death-ligand 1
Q1 Low (lowest 25%) IL-1β expression
Q4 High (highest 25%) IL-1β expression
TKI Tyrosine kinase inhibitor
TME Tumor microenvironment
TOT Time on treatment
TPS Tumor proportion score