ACE |
angiotensin-converting enzyme |
AGEs |
advanced glycation end products |
ANGII |
angiotensin II |
ARBs |
angiotensin receptor blockers |
Apo(a) |
apolipoprotein(a) |
ApoB |
apolipoprotein B-100 |
AS |
aortic stenosis |
ATP |
adenosine triphosphate |
BMP-2 |
bone morphogenetic protein-2 |
BP |
blood pressure |
CAVD |
calcific aortic valve disease |
CAVS |
calcific aortic valve stenosis |
CDH11 |
cadherin-11 |
cGMP |
cyclic guanosine monophosphate |
DPP-4 |
dipeptidyl peptidase-4 |
DRP1 |
dynamin-related protein 1 |
EndMT |
mesenchymal cells |
FGF2 |
Fibroblast Growth Factor 2 |
GIP |
glucose-dependent insulinotropic polypeptide |
GLP-1 |
glucagon-like peptide-1 |
HDL |
high-density lipoprotein |
IGF-1 |
insulin growth factor-1 |
IL-1β |
interleukin-1 beta |
IMT |
intima-media thickness |
LDL |
low-density lipoprotein |
Lp(a) |
lipoprotein(a) |
Lp-PLA2
|
lipoprotein-associated phospholipase A2
|
Lrp5 |
Low-Density Lipoprotein Receptor-Related Protein 5 |
LRR |
leucine-rich repeat |
MACE |
major adverse cardiovascular events |
MGP |
matrix Gla-protein |
MMPs |
matrix metalloproteinases |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
NLRP3 |
NOD-, LRR-, and pyrin domain-containing protein 3 |
NADPH |
nicotinamide adenine dinucleotide phosphate |
NO |
nitric oxide |
NOD |
nucleotide-binding oligomerization domain |
NOX2 |
NADPH oxidase 2 |
OPG |
osteoprotegerin |
Ox-LDL |
oxidized low-density lipoprotein |
OxPL-apoB |
oxidized phospholipids associated with apolipoprotein B |
OxPL |
oxidized phospholipids |
PCSK9 |
proprotein convertase subtilisin/kexin type 9 |
RAAS |
renin-angiotensin-aldosterone system |
RANK |
receptor activator of nuclear factor kB |
RANKL |
receptor activator of nuclear factor kB ligand |
ROS |
reactive oxygen species |
RUNX2 |
runt-related transcription factor 2 |
sGC |
soluble guanylate cyclase |
TAVI |
transcatheter aortic valve implantation |
TNF-α |
tumor necrosis factor alpha |
TZDs |
thiazolidinediones |
UTP |
uridine triphosphate |
VECs |
endothelial valve cells |
VICs |
valvular interstitial cells |
VKAs |
vitamin K antagonists |
VSMCs |
vascular smooth muscle cells |