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. 2025 Aug 22;26(17):8163. doi: 10.3390/ijms26178163
ACE angiotensin-converting enzyme
AGEs advanced glycation end products
ANGII angiotensin II
ARBs angiotensin receptor blockers
Apo(a) apolipoprotein(a)
ApoB apolipoprotein B-100
AS aortic stenosis
ATP adenosine triphosphate
BMP-2 bone morphogenetic protein-2
BP blood pressure
CAVD calcific aortic valve disease
CAVS calcific aortic valve stenosis
CDH11 cadherin-11
cGMP cyclic guanosine monophosphate
DPP-4 dipeptidyl peptidase-4
DRP1 dynamin-related protein 1
EndMT mesenchymal cells
FGF2 Fibroblast Growth Factor 2
GIP glucose-dependent insulinotropic polypeptide
GLP-1 glucagon-like peptide-1
HDL high-density lipoprotein
IGF-1 insulin growth factor-1
IL-1β interleukin-1 beta
IMT intima-media thickness
LDL low-density lipoprotein
Lp(a) lipoprotein(a)
Lp-PLA2 lipoprotein-associated phospholipase A2
Lrp5 Low-Density Lipoprotein Receptor-Related Protein 5
LRR leucine-rich repeat
MACE major adverse cardiovascular events
MGP matrix Gla-protein
MMPs matrix metalloproteinases
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
NLRP3 NOD-, LRR-, and pyrin domain-containing protein 3
NADPH nicotinamide adenine dinucleotide phosphate
NO nitric oxide
NOD nucleotide-binding oligomerization domain
NOX2 NADPH oxidase 2
OPG osteoprotegerin
Ox-LDL oxidized low-density lipoprotein
OxPL-apoB oxidized phospholipids associated with apolipoprotein B
OxPL oxidized phospholipids
PCSK9 proprotein convertase subtilisin/kexin type 9
RAAS renin-angiotensin-aldosterone system
RANK receptor activator of nuclear factor kB
RANKL receptor activator of nuclear factor kB ligand
ROS reactive oxygen species
RUNX2 runt-related transcription factor 2
sGC soluble guanylate cyclase
TAVI transcatheter aortic valve implantation
TNF-α tumor necrosis factor alpha
TZDs thiazolidinediones
UTP uridine triphosphate
VECs endothelial valve cells
VICs valvular interstitial cells
VKAs vitamin K antagonists
VSMCs vascular smooth muscle cells