ABI	ankle–brachial index
AGE	advanced glycation end-product
AKT1	an isoform of the serine/threonine protein kinase B
BMP	bone morphogenetic protein
CEAP	Clinical–Etiological–Anatomical–Pathophysiological classification
CFF	cell-free filtrate
CVD	chronic venous disease
CircRNA	circular RNA
CW	chronic wound
CWF	chronic-wound-derived fibroblast
DAMPs	damage-associated molecular patterns
DFU	diabetic foot ulcer
DNMT	DNA methyltransferase
ECM	extracellular matrix
FGF	fibroblast growth factor
GT	granulation tissue
H/E	hematoxylin/eosin
HDAC	histone deacetylase
ICAM-1	interstitial cell adhesion molecule 1
IGF-I	insulin-like growth factor
JNK	c-Jun N-terminal kinase
lncRNA	long non-coding RNA
miRNA	microRNA
MMP	matrix metalloproteinase
NET	neutrophil extracellular trap
NF-κB	nuclear factor kappa B
NLRP3	NOD-like receptor protein 3
Nrf2	nuclear respiratory factor 2
OS	oxidative stress
PAMPs	pathogen-associated molecular patterns
PI	pressure injury
PI3	phosphatidylinositol 3-kinase
PKC	protein kinase C
PTEN	phosphatase and tensin homolog
ROS	reactive oxygen species
SASP	senescence-associated secretory phenotype
TGF-β1	transforming growth factor beta 1
TNF-α	tumor necrosis factor alpha
VCAM-1	vascular cell adhesion molecule 1
VEGF	vascular endothelial growth factor
VLU	venous leg ulcer