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. 2025 Aug 29;14(17):6122. doi: 10.3390/jcm14176122

Table 1.

Comparison of donor candidate backgrounds.

Group Overall Secondary
Research Enrollment
Virtual Cross-Match Group Excluded Group p-Value * Living Kidney Transplantation (2012–2021) p-Value **
n 117 80 37 14,354
Age (years) 56.5 ± 12.1 56.3 ± 11.0 56.9 ± 14.5 0.815 58.0 N/A
Age distribution 20–29 1 0 1 0.026 128 0.138
30–39 6 5 1 672
40–49 20 16 4 2314
50–59 38 31 7 4003
60–69 39 20 19 4862
70–79 9 7 2 1919
80- 2 1 1 75
Sex (male/female) 81:35 58:22 23:13 0.386 5213:9141 <0.001
Relationship (spouse(husband/wife)/parent/sibling/other) 81(70:11):17:13:6 59(51:8):11:6:4 22(19:3):6:7:2 0.131 5589:4885:1433:2447 <0.001
Hypertension (yes/no) 20:89 17:61 3:28 0.018 2481:9202 0.890
Diabetes mellitus (yes/no) 10:101 9:69 1:32 0.058 568:11,109 0.014
s-Cre (mg/dL) 0.85 ± 0.62 0.82 ± 0.14 0.93 ± 1.15 0.430 0.70 N/A
eGFR (mL/min/1.73 m2) 74.4 ± 14.5 72.6 ± 12.3 78.3 ± 18.4 0.074 N/A N/A

* Comparison between the virtual cross-match group and the excluded group. ** Comparison between the virtual cross-match group and living kidney transplantation (2012–2021). N/A, not available. Bolded numbers indicate significant differences.