Table 2.
Comparison of recipient candidate background.
| Overall Secondary Research Enrollment |
Virtual Cross-Match Group | Excluded Group | p Value * | Living Kidney Transplantation (2012–2021) | p Value ** | ||
|---|---|---|---|---|---|---|---|
| 117 | 80 | 37 | 14,354 | ||||
| Age (years) | 52.1 ± 10.6 | 51.2 ± 10.7 | 53.9 ± 10.3 | 0.201 | 47.2 | N/A | |
| Age distribution | 0–9 | 1 | 1 | 0 | 0.166 | 252 | 1.000 |
| 10–19 | 0 | 0 | 0 | 430 | |||
| 20–29 | 1 | 1 | 0 | 1156 | |||
| 30–39 | 18 | 10 | 8 | 2388 | |||
| 40–49 | 27 | 23 | 4 | 3415 | |||
| 50–59 | 46 | 31 | 15 | 3199 | |||
| 60–69 | 24 | 14 | 10 | 2922 | |||
| 70- | 0 | 0 | 0 | 592 | |||
| Sex (male/female) | 22:95 | 15:65 | 7:30 | 1.000 | 9192:5162 | <0.001 | |
| Blood type (compatible/incompatible) | 65:49 | 45:35 | 20:14 | 0.839 | 8671:4033 | 0.029 | |
| HLA mismatch | 0 | 2 | 0 | 2 | 0.024 | 535 | 0.024 |
| 1 | 0 | 0 | 0 | 682 | |||
| 2 | 6 | 2 | 4 | 2099 | |||
| 3 | 30 | 17 | 13 | 3458 | |||
| 4 | 20 | 16 | 4 | 1607 | |||
| 5 | 41 | 30 | 11 | 1743 | |||
| 6 | 18 | 15 | 3 | 953 | |||
| Direct XM T warm (positive/negative) | 50:54 | 32:39 | 18:15 | 0.669 | 81:11,248 | <0.001 | |
| Direct XM B warm (positive/negative) | 58:39 | 37:30 | 21:9 | 0.044 | 265:11,007 | <0.001 | |
| Flow XM T (positive/negative) | 86:21 | 61:14 | 25:7 | 0.717 | 501:11,026 | <0.001 | |
| Flow XM B (positive/negative) | 102:2 | 73:0 | 29:2 | 0.083 | 990:10,147 | <0.001 | |
| Flow PRA class1 | 0–less than 20% | 9 | 6 | 3 | 0.847 | 5276 | <0.001 |
| 20–less than 40% | 6 | 3 | 3 | 180 | |||
| 40–less than 60% | 8 | 6 | 2 | 113 | |||
| 60–less than 80% | 9 | 7 | 2 | 70 | |||
| 80–100% | 17 | 12 | 5 | 66 | |||
| Flow PRA class2 | 0–less than 20% | 13 | 12 | 1 | 0.101 | 5334 | <0.001 |
| 20–less than 40% | 2 | 2 | 0 | 134 | |||
| 40–less than 60% | 9 | 6 | 3 | 72 | |||
| 60–less than 80% | 6 | 6 | 3 | 60 | |||
| 80–100% | 15 | 7 | 8 | 66 | |||
| DSA (positive/negative) | 117:0 | 80:0 | 37:0 | 1.000 | 777:5837 | <0.001 | |
* Comparison between the virtual cross-match group and the excluded group. ** Comparison between the virtual cross-match group and living kidney transplantation (2012–2021). N/A, not available. Bolded numbers indicate significant differences.