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. 2025 Sep 5;30(17):3628. doi: 10.3390/molecules30173628
3-HK 3-hydroxykynurenine
ABG-001 tetradecyl 2,3-dihydroxybenzoate
acdA acyl-coenzyme A dehydrogenase
AChE acetylcholinesterase
ACSBG1 acyl-CoA synthetase, bubblegum family, member 1 gene
AD Alzheimer’s disease
ADRA2B adrenoceptor alpha 2B
AhR aryl hydrocarbon receptor
Apo-E4 apolipoprotein E4
APP amyloid-beta precursor protein
ArAT aromatic amino acid aminotransferase
β-amyloid
BBB blood–brain barrier
BChE butyrylcholinesterase
BDNF: brain-derived neurotrophic factor
CSF cerebrospinal fluid
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP3A cytochrome P450, family 3, subfamily A
EC50 half maximal effective concentration
ECM extracellular matrix
EDSS Expanded Disability Status Scale
fldBC phenyllactate dehydratase BC
FOXO3a forkhead box O3
GPR G-protein-coupled receptor
HCAR3 hydroxycarboxylic acid receptor 3
HD Huntington’s disease
HK2 hexokinase 2
Hsc70 heat shock cognate 70 kDa protein
IA indoleacrylic acid
IAA indole-3-acetic acid
IDO1 indoleamine 2,3-dioxygenase 1
IFN-γ interferon gamma
IL-1β/4/6/10 interleukin 1β/4/6/10
IL4I1 interleukin 4-induced 1
ILA indolelactic acid
ILDH indole-lactate dehydrogenase
iNOS inducible nitric oxide synthase
IPA indole-3-propionic acid
IPAM indolepropionamide
iPROACT-pilot Indole-3-PROpionic Acid Clinical Trials-a Pilot Study
IPyA indole-3-pyruvic acid
JAK1/2 Janus kinase 1/2
KATs kynurenine aminotransferases
KMO kynurenine 3-monooxygenase
KP kynurenine pathway
KYNA kynurenic acid
LC3 light chain 3
LPS lipopolysaccharide
MAO monoamino-oxidase
MCAO middle cerebral artery occlusion
MCP-1/CCL2 monocyte chemoattractant protein-1
MMP matrix metalloproteinase;
NAD nicotinamide adenine dinucleotide
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
NGF nerve growth factor
NLRP3 NLR family pyrin domain containing 3
NMDA N-methyl-D-aspartate type
NR1I2 nuclear receptor subfamily 1 group I member 2 gene
Oatp1a4 organic anion-transporting polypeptide 1a4
PD Parkinson’s disease
PKM2 pyruvate kinase muscle isozyme
PPARα peroxisome proliferator-activated receptor α
PXR pregnane X receptor
QUIN quinolinic acid
RAGE receptor for advanced glycation end-products
ROS reactive oxygen species
SCD2/3 stearoyl-CoA desaturase 2/3 gene
SIRT1 sirtuin 1
STAT3/6 signal transducer and activator of transcription 3/6
TAA Trp aminotransferase
TDO tryptophan 2,3-dioxygenase
TGF-1 transforming growth factor β1
Th17 T helper 17 cells
TIARSCeD Tryptophan for Impaired AhR Signaling in Celiac Disease
TLRs Toll-like receptors
TNF-α tumor necrosis factor-α
Treg regulatory T cells
Trp tryptophan
α7nAChR α-7 nicotinic acetylcholine receptor