2-AIBA	2-aminoisobutyric acid
2-CIMA	2-chloromalonaldehyde
ACN	Acetonitrile
AEX	Anion-exchange chromatography
API	Active pharmaceutical ingredients
AQbD	Analytical quality by design
CAD	Charged aerosol detector
DAD	Diode array detector
DoE	Design of experiments
ESI	Electrospray
ELSD	Evaporative light-scattering detector
EP	European Pharmacopoeia
FA	Formic acid
FLD	Fluorescence detector
GPC	Gel permeation chromatography
HILIC	Hydrophilic interaction chromatography
HPLC	High-performance liquid chromatography
ICH	International Council for Harmonization
IPRP	Ion-pair reversed phase
LOD	Limit of detection
LOQ	Limit of quantitation
MS	Mass spectrometry
NA	Not applicable
NH4Ac	Ammonium acetate
NHS	N-hydroxysuccinimide
QTOF	Quadrupole time-of-flight
RP	Reversed phase
RP-HPLC	Reversed-phase high-performance liquid chromatography
SIM	Selected ion monitoring
SPE	Solid phase extraction
sulfo-NHS	N-hydroxysulfosuccinimide
TFA	Trifluoroacetic acid
TLC	Thin-layer chromatography
USP	United States Pharmacopeia