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. 2025 Jun 20;111(9):6362–6373. doi: 10.1097/JS9.0000000000002686

Table 4.

Detailed results of the meta-analysis

Item Time point Number of study Early group Late group Heterogeneity (I2, P) Heterogeneity between groups P
n WMD (95% CI) Heterogeneity (I2, P) n WMD (95% CI) Heterogeneity (I2, P)
ΔVAS scores for back pain Within postoperative 3 days 5 42 2.90 (1.96–3.84) NAa 201 2.36 (1.64–3.07) 89.8%–<0.001 86.5%, <0.001 0.368
3 months 7 72 3.26 (2.72–3.80) 0.0%, 0.758 270 2.98 (2.29–3.67) 94.1%, <0.001 91.3%, <0.001 0.529
6 months 4 42 3.57 (2.65–4.49) NAa 104 3.27 (2.29–4.25) 93.7%, <0.001 90.7%, <0.001 0.663
12 months 5 72 3.49 (2.95–4.03) 0.0%, 0.654 205 3.01 (2.16–3.85) 87.6%, <0.001 79.1%, <0.001 0.345
ΔVAS scores for leg pain Within postoperative 3 days 10 146 6.87 (6.26–7.48) 84.8%, 0.001 341 4.47 (3.56–5.37) 96.9%, <0.001 98.0%, <0.001 <0.001
3 months 10 72 6.45 (4.64–8.26) 94.2%, <0.001 510 5.34 (4.46–6.21) 98.3%, <0.001 98.1%, <0.001 0.279
6 months 8 74 7.59 (7.20–7.98) 32.3%, 0.224 290 5.67 (4.93–6.41) 98.4%, <0.001 96.8%, <0.001 <0.001
12 months 8 72 6.58 (4.31–8.84) 96.5%, <0.001 205 5.68 (4.76–6.59) 96.6%, <0.001 97.2%, <0.001 0.47
ΔODI values Within postoperative 3 days 7 114 26.68 (13.07–40.30) 97.6%, <0.001 188 32.87 (25.24–40.50) 95.9%, <0.001 96.2%, <0.001 0.437
3 months 8 72 45.09 (32.54–57.65) 90.6%, <0.001 321 44.92 (40.31–49.54) 94.1%, <0.001 92.8%, <0.001 0.98
6 months 9 74 42.51 (13.74–71.28) 99.3%, <0.001 244 43.67 (37.77–49.57) 97.3%, <0.001 98.0%, <0.001 0.938
12 months 8 72 54.56 (41.44–67.68) 92.5%, <0.001 324 48.84 (46.50–51.17) 43.6%, 0.131 83.9%, <0.001 0.4
Complication rate NA 13 176 0.03 (0.01–0.06) 0.00%, 0.44 439 0.07 (0.02–0.12) 71.3%, <0.001 64.3%, <0.001 0.164
MacNab criteria 12 134 0.91 (0.85–0.95) NAb 438 0.90 (0.87–0.93) NAb NA 0.884

NA, not available; ΔVAS scores, the reduction in VAS score from preoperative to postoperative periods; ΔODI values, the reduction in ODI values from preoperative to postoperative periods.

a

Only one study was included.

b

I2 = 0.