Table 4.

Characteristics classified by pathological complete response

	Pathological complete response		P-value
	No (<100%)	Yes (100%)
	n = 24	n = 7
RECIST
CR	0(0%)	7(100%)	P<0.001
PR	16(66.7%)	0(0%)
SD	8(33.3%)	0(0%)
PD	0(%)	0(0%)
Age
≥65	8(33.3%)	1(14.3%)	0.639
<65	16(66.7%)	6(85.7%)
Sex
Male	18(75%)	5(71.4%)	1
Female	6(25%)	2(28.6%)
Smoking status
Current or former smoker	14(58.3%)	2(28.6%)	0.22
Never smoked	10(41.7%)	5(71.4%)
ECOG Physical Score
0	15(62.5%)	3(42.9%)	0.413
1	9(37.5%)	4(57.1%)
Preoperative nodal stage
N1	17(70.8%)	4(57.1%)	0.652
N2	7(29.2%)	3(42.9%)
Downstaging of nodal status in patients with N2 or N1 at baseline
N2 to N2 or N1 to N1	15(62.5%)	0(0%)	0.007
N2 to N1/N0 or N1 to N0	9(37.5%)	7(100%)
Stage at presentation
IIA	10(41.6%)	2(28.6%)	0.757
IIB	7(29.2%)	2(28.6%)
IIIA	7(29.2%)	3(42.8%)
PD-L1 expression
>1%	10(41.6%)	6(85.8%)	0.083
≤1%	14(58.4%)	1(14.2%)
TMB (Tumor mutational burden)
>5.7	9(37.5%)	6(85.8%)	0.037
≤5.7	15(62.5%)	1(14.2%)