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Phenotype of A549 cells infected with serotype M1 GAS strains. Scanning electron micrographs of A549 cells infected for 1 h with (A) MGAS5005, (B) MGAS5005sic, or (C) MGAS5005sic in the presence of 10 μg/ml of Sic. Note that there are fewer A549 cells visible in A and C because of cell flattening caused by Sic. (Bar = 10 μm.)
