Table 1.
ZIP1 immuno-positivity of glandular components in tissue sections of confirmed cases of prostate cancer.
Case no. | Grade | ZIP1 IHC scorea | |||
Normal | PIN | BPH | Malignant | ||
1 | 3 | +++ | +++ | Negative | |
2 | 3 | + | ++ | + | |
3 | 1 | Negative | + | Negative | |
4 | 2 | + | Negative | ||
5 | 2 | Negative | Negative | ||
6 | 1 | Negative | +++ | Negative | |
7 | 2 | ++ | + | + | |
8 | 1 | +++ | + | ||
9 | 1 | ++ | +++ | Negative | |
10 | 2 | +++ | Negative | ||
11 | 1 | ++ | Negative | ||
12 | 2 | Negative | Negative | ||
13 | 1 | ++ | + | ||
14 | 1 | + | Negative | ||
15 | 1 | + | Negative | ||
16 | 1 | Negative | + | Negative | |
17 | 2 | +++ | + | ||
18 | 1 | + | ++ | + | |
19 | 1 | + | Negative | ||
20 | 1 | + | Negative | ||
21 | 2 | + | +++ | + | |
22 | 1 | Negative | Negative | ||
NEG ZIP1 IHC | 3/22 (14%) | 15/22 (68%)* | |||
SCORES > + | 3/4 | 0/6 | 11/22 | 0/22* | |
MEAN SCOREb | 1.75 | 0.6 | 1.68(1.09) | 0.32(0.48)* |
a Scoring of immunoreactivity was done as follows: negative, no positive cells; score +, <10% positive cells; score ++, 10–50% positive cells; score +++, >50% positive cells
b MEAN SCORE: MEAN(SD) for each group was obtained by the sum of the +'s/number of cases.
* P < 0.01; BPH VS MALIGNANT GROUPS