Table 2. Univariate and multivariate analyses of 1,463 gGIST patients for OS.
| Variables | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| Age | 0.614 (0.371–1.014) | 0.057 | |||
| Gender | 0.776 (0.484–1.245) | 0.29 | |||
| Tumor location | 1.222 (0.832–1.795) | 0.31 | |||
| Tumor size | 2.377 (1.828–3.092) | <0.001 | 1.800 (1.282–2.527) | 0.001 | |
| Mitotic count | 2.747 (2.094–3.604) | <0.001 | 2.189 (1.560–3.071) | <0.001 | |
| Tumor necrosis | 0.260 (0.152–0.445) | <0.001 | 1.986 (1.112–3.544) | 0.02 | |
| NIH risk categories | 3.433 (2.470–4.771) | <0.001 | |||
CI, confidence interval; gGIST, gastric gastrointestinal stromal tumor; HR, hazard ratio; NIH, National Institutes of Health; OS, overall survival.