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. 2025 Feb 25;9(12):3090–3103. doi: 10.1182/bloodadvances.2024013953

Table 5.

Longitudinal measurement of pain-related disease burden after HCT

Domain Measure Assessment
Health care utilization Emergency room visits/hospitalizations for pain Document yearly until return to normal
Opioid use Monthly morphine equivalents
Patient-reported pain intensity PROMIS 25 profile in children, PROMIS 29 profile in adults
Patient-reported pain interference PROMIS 25 profile in children, PROMIS 29 profile in adults
Identification of high-impact chronic pain Graded chronic pain scale revised

PROMIS 25, Patient Reported Outcomes Measurement System 25.

For further details on pain-related measurements.119