Table 1. Clinical Demographic Profile Among CHD and Controls Groups.
A retrospective collection of plasma samples from patients with diagnosed coronary heart disease (CHD) and healthy controls were included in the study. The two groups were matched based on male/female ratio and total plasma cholesterol. Inclusion criteria comprised patients who self-reported white/European race/ethnicity and non-smoker status, confirmed by referencing medical records to ensure non-use of lipid-lowering medications. Comparative analysis of total control to total CHD revealed that CHD patients were significantly older and had higher BMIs and elevated plasma Preβ HDL concentrations, while otherwise plasma lipids levels showed no significant differences between the groups. Significance between Control and CHD groups was determined using a t-test with p <0.05.
| Control (N=67) | Coronary Heart Disease (N=41) | Significance | |||
|---|---|---|---|---|---|
| Male/Female |
M: N = 29 (43%)
F: N = 38 (57%) |
M: N =19 (46%)
F: N = 22 (54%) |
No | ||
| Average (S.D.) | Range | Average (S.D.) | Range | ||
| Age | 35.3 (11.3) | 18–58 | 50.7 (7.9) | 29–61 | Yes |
| Body Mass Index (kg/m2) | 24.9 (4.3) | 18–42 | 26.9 (5.5) | 18.3–47.4 | Yes |
| Total Cholesterol (mg/dL) | 184.1 (36.3) | 68–285 | 193.5 (57.8) | 102–335 | No |
| Triglycerides (mg/dL) | 85.8 (39) | 33–276 | 98.0 (48.1) | 33–270 | No |
| LDL-Cholesterol (mg/dL) | 102.8 (34.3) | 17–189 | 116.4 (52.9) | 21–243 | No |
| HDL-Cholesterol (mg/dL) | 64.0 (17.8) | 25–101 | 59.6 (22.3) | 29–107 | No |
| hsCRP (mg/L) | 2.8 (2.7) | 0.01–18.0 | 2.4 (3) | 0.01–13.0 | No |
| Preβ HDL (mg/dL apoA1) | 10.2 (4.0) | 3.7–20.3 | 13.5 (5.4) | 3.7–25.6 | Yes |