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. Author manuscript; available in PMC: 2025 Sep 15.
Published in final edited form as: Proc (Int Conf Comput Sci Comput Intell). 2025 Aug 29;2507:139–153. doi: 10.1007/978-3-031-94950-0_13

Table 1. Clinical Demographic Profile Among CHD and Controls Groups.

A retrospective collection of plasma samples from patients with diagnosed coronary heart disease (CHD) and healthy controls were included in the study. The two groups were matched based on male/female ratio and total plasma cholesterol. Inclusion criteria comprised patients who self-reported white/European race/ethnicity and non-smoker status, confirmed by referencing medical records to ensure non-use of lipid-lowering medications. Comparative analysis of total control to total CHD revealed that CHD patients were significantly older and had higher BMIs and elevated plasma Preβ HDL concentrations, while otherwise plasma lipids levels showed no significant differences between the groups. Significance between Control and CHD groups was determined using a t-test with p <0.05.

Control (N=67) Coronary Heart Disease (N=41) Significance
Male/Female M: N = 29 (43%)
F: N = 38 (57%)
M: N =19 (46%)
F: N = 22 (54%)
No
Average (S.D.) Range Average (S.D.) Range
Age 35.3 (11.3) 18–58 50.7 (7.9) 29–61 Yes
Body Mass Index (kg/m2) 24.9 (4.3) 18–42 26.9 (5.5) 18.3–47.4 Yes
Total Cholesterol (mg/dL) 184.1 (36.3) 68–285 193.5 (57.8) 102–335 No
Triglycerides (mg/dL) 85.8 (39) 33–276 98.0 (48.1) 33–270 No
LDL-Cholesterol (mg/dL) 102.8 (34.3) 17–189 116.4 (52.9) 21–243 No
HDL-Cholesterol (mg/dL) 64.0 (17.8) 25–101 59.6 (22.3) 29–107 No
hsCRP (mg/L) 2.8 (2.7) 0.01–18.0 2.4 (3) 0.01–13.0 No
Preβ HDL (mg/dL apoA1) 10.2 (4.0) 3.7–20.3 13.5 (5.4) 3.7–25.6 Yes