TABLE 2.

Gait, WOMAC, and COMP data at baseline and 6-month follow-up

Variable	Baseline	Follow-up	P
KAM1 (%Bw × Ht)	2.67 ± 0.76	2.47 ± 0.75	<.001
KAM impulse (%Bw × Ht × s)	1.06 ± 0.36	0.99 ± 0.35	.009
Walking speed (m/s)	1.20 ± 0.14	1.22 ± 0.16	.30
WOMAC Pain	75.5 ± 15.1	75.3 ± 21.4	.95
WOMAC Stiffness	64.5 ± 17.8	65.1 ± 22.7	.95
WOMAC Function	79.6 ± 18.0	81.9 ± 18.1	.78
Resting COMP (ng/mL)	2.70 ± 1.98	2.61 ± 1.73	.41
3.5-hour COMP (% of resting)	84.4 ± 11.1	82.5 ± 9.1	.52
5.5-hour COMP (% of resting)	79.4 ± 13.3	84.5 ± 13.2	.10

Note: P values presented are from respective paired Student’s t tests or Wilcoxon signed-rank tests (for nonnormally distributed data). Data presented as mean ± standard deviation. KAM1, KAM impulse, and walking speed presented as control shoe at baseline and variable-stiffness shoe at follow-up.

Abbreviations: COMP, cartilage oligomeric matrix protein; KAM, knee adduction moment; KAM1, first peak KAM; WOMAC, Western Ontario and McMaster Universities.