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. 2025 Aug 11;22(14):3763–3778. doi: 10.7150/ijms.119142

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Functional validation of LINC01605 in TNBC. (A) RT-qPCR analysis showing differential expression of key lncRNA pairs in TNBC tissues. (B) LINC01605 expression levels in TNBC cell lines (MDA-MB-231, BT549, SUM159) and normal mammary epithelial cells (MCF10A). (C, D) RT-qPCR confirming LINC01605 knockdown efficiency in MDA-MB-231 and overexpression efficiency in BT549 cells. (E, F) CCK-8 assay demonstrating the effect of LINC01605 on cell viability. (G, H) Colony formation assay showing the impact of LINC01605 on TNBC cell proliferation. (I, J) Wound healing assay assessing the role of LINC01605 in cell migration (scale bar: 200 µm). (K, L) Transwell assay evaluating the effect of LINC01605 on cell invasion (scale bar: 50 µm). * p < 0.05, **p < 0.01, ***p < 0.001.