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Lack of hair follicle buds in skin of TRAF6−/− mouse embryos at E15.5. (A and B) Sagittal sections of embryos at E15.5. Sections were stained with hematoxylin and eosin. (C and D) Expression of β-catenin in hair follicle at E15.5. (E and F) Expression of MAdCAM-1 in hair follicle buds of embryos at E15.5 visualized by whole-mount immunostaining. TRAF6−/− mice (B, D, and F) and heterozygous littermates (A, C, and E) .
