Figure 4.

Developmental defects in skin eccrine glands in TRAF6^−/− mice. (A and B) Sections of palmar skin at day 8. Arrows and arrowheads in A indicate sweat ducts and sweat glands, respectively. (C and D) Horizontal sections of back skin at day 11. Arrowheads indicate sebaceous glands. (E and F) Sections of an eyelid. Arrows in E indicate meibomian glands. (G and H) Sections of an anal. Arrow in H indicates a significantly reduced anal gland of the TRAF6^−/− mouse. (I and J) Photographs of abdomen of a male mouse. Arrows in I indicate preputial glands. TRAF6^−/− mice (B, D, F, H, and J) and heterozygous littermates (A, C, E, G, and I).