Table 2.
Comparison of the rates of co-expression and inverse expression between different putative SA pair setsa
| Putative SA pair set | Human | Mouse | ||
|---|---|---|---|---|
| Rate of co-expression | Rate of inverse expression | Rate of co-expression | Rate of inverse expression | |
| Conserved | 60.8% (211/347) | 51.9% (180/347) | 56.8% (197/347) | 44.4% (154/347) |
| Non-conserved | 34.9% (961/2750) | 28.5% (784/2750) | 32.4% (246/759) | 28.7% (218/759) |
| x2-test | P < 10−4 | P < 10−4 | P < 10−4 | P < 10−4 |
| 3′-to-3′ | 51.5% (561/1090) | 41.9% (457/1090) | 55.3% (293/530) | 44.2% (234/530) |
| 5′-to-5′ | 34.2% (227/664) | 29.2% (194/664) | 28.7% (85/296) | 26.7% (79/296) |
| embedded | 28.6% (384/1343) | 23.3% (313/1343) | 23.2% (65/280) | 21.1% (59/280) |
| x2-test (3′-to-3′ versus 5′-to-5′; 3′-to-3′ versus embedded) | P < 10−4; P < 10−4 | P < 10−4; P < 10−4 | P < 10−4; P < 10−4 | P < 10−4; P < 10−4 |
aNote that, all P-values far <10−4 are also shown as P < 10−4. The co-expressed putative SA pairs were defined as those in which the two partners are coordinately expressed in the same tissues more often than expected by chance; the inversely expressed putative SA pairs were defined as those with both an inverse expression pattern between two partners and a significantly greater change of the relative expression ratio of sense to antisense between two states of the same tissues than expected by chance; the conserved putative SA pairs are the pairs conserved as putative SA form in both human and mouse genomes. See Materials and Methods for more details.