Figure 3.

Classification of predicted alternative splice events. (A) Skipping of a single exon. (B) Skipping of multiple consecutive exons (shown here for two exons). (C) Intron retention (shown as red dashed box). (D) Hidden exon: the algorithm found an ORF (start and stop codon are indicated) within an intron that encodes a Pfam domain (blue box) which indicates the existence of a hidden exon (gray dashed box). (E) Complex events involve any combination of (A–D). Here, we show an example with two skipped exons. Exons are shown as gray boxes and dashed lines indicate the splicing patterns.