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. 2002 Jun 19;99(13):8892–8897. doi: 10.1073/pnas.092259799

Figure 5.

Figure 5

Effect of anti-Fas Ab on cell viability determined in cells treated with annexin V and PI. (a) Anti-Fas Ab caused a time- and concentration-dependent fall in cell viability. (b) Treatment with anti-Fas Ab led to apoptosis (cells annexin V positive, PI negative). (c) Treatment with anti-Fas Ab led to necrosis (cells annexin V positive, PI positive). (d) l-NAME (500 μM) alone had no effect on cell viability but significantly enhanced cell mortality 3 h after treatment with anti-Fas Ab (10 ng/ml). n = 5; *, P < 0.05.