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. 2002 Jun 17;99(13):8898–8902. doi: 10.1073/pnas.132067399

Figure 1.

Figure 1

Functional activity of Spiegelmers NOX 1255 and NOX 1257 in cell culture. Chinese hamster ovary cells expressing the human GnRH receptor are stimulated with GnRH (a) and Buserelin (b) after preincubation with increasing concentrations of Spiegelmer NOX 1255 (■) and NOX 1257 (▴). The results show the percentage of fluorescence signal normalized to the signal obtained with the lowest Spiegelmer concentration (e.g., 3,00E-10 = 3.00 × 10−10). The experiments were done in triplicate, and the value shown is the average.