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Enumeration of endothelial cell nuclei above the ILM in sections of whole eyes from hyperoxia-treated P17 mouse pups. These quantitative results agree with the qualitative assessment (see Fig. 1), that vector-mediated expression of PEDF (a) or K1K3 (b) reduces the level of oxygen-induced NV. (c) Statistical analysis of the paired eyes shows a significant difference between control and treated eyes for both PEDF and K1K3 (P < 0.0000002).
