Skip to main content
. Author manuscript; available in PMC: 2025 Sep 17.
Published in final edited form as: Biol Psychiatry. 2023 Aug 1;94(3):189–190. doi: 10.1016/j.biopsych.2023.04.012

Figure 1.

Figure 1.

Chronic stress exposure (“trauma”) led to enduring (i.e., during protracted abstinence) sensitization to subsequent stress-induced and stress-related cue-induced relapse to alcohol-seeking behavior, effects that were accompanied by changes in the hypothalamic oxytocin system. Systemic oxytocin administration blocked the sensitized relapse to stress-induced alcohol-seeking behavior.