Table 1.
Adenoma source | Probe | N | FISH signals per nucleus
|
|
---|---|---|---|---|
Normal tissue | Tumor tissue | |||
B6Min/+ ♂ | Chr. X-specific | 4 | 1.04 ± 0.02 | 1.06 ± 0.02* |
B6Min/+ ♀ | Chr. X-specific | 5 | 1.68 ± 0.03 | 1.61 ± 0.01 |
B6Min/+ | Chr. 18-specific | 23 | 1.65 ± 0.08 | 1.63 ± 0.07† |
B6Min/+ | Apc locus | 17 | 1.69 ± 0.06 | 1.67 ± 0.04 |
B6Min/+ | Chr. 4-specific | 14 | 1.53 ± 0.06 | 1.52 ± 0.04 |
B6Min/+ | Chr. 7-specific | 5 | 1.59 ± 0.03 | 1.68 ± 0.04 |
Chr., chromosome.
P > 0.15 when compared with corresponding normal tissue (Wilcoxon Rank Sum analysis), and P < 0.01 when compared with tumor or normal tissue from B6 Min/+ ♀ tumors.
All autosomes examined are present in two copies.