The genotypes of H5N1 reassortants and their derivation from 1997 to 2001. The eight gene segments in each schematic virus particle are represented in the order (top to bottom) PB2, PB1, polymerase (PA), hemagglutinin (HA), nucleoprotein (NP), neuraminidase (NA), matrix (M), and nonstructural (NS) genes. A different color is used to represent each distinct virus lineage. The virus abbreviations used are: H9N2 (G1), Quail/Hong Kong/G1/97; H6N1 (W312), Teal/Hong Kong/W312/97; H5N1 Gs/Gd, Goose/Guangdong/1/96; H9N2/Y280, Chicken/Hong Kong/Y280/97; and H5N1/97, A/Hong Kong/156/97-like viruses. Abbreviations used for poultry are explained in the footnote. The reassortment events that most likely led to the genesis of the pathogenic viruses of 1997 (H5N1/97) are included for reference. ? denotes that genotype A viruses have not so far been isolated from aquatic poultry in Hong Kong.