. Author manuscript; available in PMC: 2025 Sep 18.

Published before final editing as: J Physiol. 2025 Jan 14:10.1113/JP287573. doi: 10.1113/JP287573

Table 4.

DEPs identified for predicted upstream regulator: PPARGC1A in the frontal cortex of HMGCS2 KD-EX compared with SCR-EX 1 h after an acute bout of exercise.

Symbol	Protein name/description	Log₂(fold change)	False discovery rate (q-value)
ATP5F1B	ATP synthase F1 subunit beta	−0.0904	0.0001
CACNA1H	Calcium voltage-gated channel subunit alpha1 H	0.6431	0.0367
CACNA2D2	Calcium voltage-gated channel auxiliary subunit alpha2delta 2	0.4035	0.0179
COX7B	Cytochrome c oxidase subunit 7B	0.4005	0.0287
DLAT	Dihydrolipoamide S-acetyltransferase	−0.0171	0.0055
MAPT	Microtubule-associated protein tau	0.4641	0.0179
MFN2	Mitofusin 2	−0.0300	0.0010
NDUFV1	NADH:ubiquinone oxidoreductase core subunit V1	−0.0093	0.0184
NDUFV2	NADH:ubiquinone oxidoreductase core subunit V2	0.0611	0.0370
PRKAA2	Protein kinase AMP-activated catalytic subunit alpha 2	0.0750	0.0075
SOD2	Superoxide dismutase 2	−0.0374	0.0219