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. 2002 Jun 25;99(13):9026–9030. doi: 10.1073/pnas.142039099

Figure 4.

Figure 4

CPP in wild-type (wt) mice or mice carrying a mutation in mPer1 and mPer2 genes. Cocaine-induced place conditioning engendered opposite responses in Per1 mutant and Per2 mutant mice. Data are given as mean ± SEM of difference between time on cocaine-paired and saline-paired side. One-way ANOVA revealed significant differences for the factor genotype: F(2,63) = 5.65, P = 0.005. Post hoc analysis showed differences between wt and Per1 mutant (P = 0.029) and no difference between wt vs. Per2 mutant (P = 0.45), Per1 mutant vs. Per2 mutant P = 0.026. * indicates a significant difference to wt mice, P < 0.05.