Table 1.
Descriptive Statistics Of Demographic Variables By Heart Failure (HF) Status
| No HFa (N=6270) | All HF (N=292) | HF Subtypes Defined By Ejection Fraction Status |
||||
|---|---|---|---|---|---|---|
| Variable, Mean (SD) or % | HFrEF (N=128) | HFpEF (N=110) | HFunk (N=54) | |||
|
| ||||||
| Age (years) | 62 (1O) | 69 (9)* | 67 (9)* | 69 (8)* | 70 (9)* | |
| BMI (kg/m 2 ) | 28.3 (5.4) | 29.8 (5.9)* | 29.4 (5.4)* | 29.6 (5.6)* | 31.0 (7.4)* | |
| LDL Cholesterol (mg/dL) | 117 (31) | 114 (33) | 114 (34) | 112 (31) | 114 (33) | |
| Non-HDL Cholesterol (mg/dL) | 143 (35.88) | 141 (36) | 142 (37) | 139 (35) | 142 (34) | |
| HDL Cholesterol (mg/dL) | 51.1 (14.9) | 48.6 (13.9)* | 47.6 (12.8)* | 49.9 (14.1) | 48.6 (15.8) | |
| Triglycerides (mg/dL) | 131 (88) | 142 (113) | 136 (78) | 146 (154) | 145 (84) | |
| eGFR (ml/min/1.73 m2) | 78.4 (16.1) | 71.9 (18.5)* | 71.4 (18.2)* | 72.6 (18.4)* | 71.7 (19.3)* | |
| Gender | Male % | 46.6 | 58.9* | 69.5* | 49.1 | 53.7 |
| Site | WFU% | 15.4 | 24.0 | 20.3 | 30.9 | 18.5 |
| COL% | 16.0 | 17.5 | 17.2 | 16.4 | 20.4 | |
| JHU% | 15.7 | 12.0 | 13.3 | 8.2 | 16.7 | |
| UMN% | 15.7 | 18.5 | 21.9 | 18.2 | 11.1 | |
| NWU% | 17.5 | 12.7 | 14.8 | 10.9 | 11.1 | |
| UCLA% | 19.7 | 15.4 | 12.5 | 15.5 | 22.2 | |
| Race /Ethnicity | White % | 38.5 | 39.7 | 37.5 | 46.4 | 31.5 |
| Chinese American % | 12.3 | 7.2 | 3.1 | 10.9 | 9.3 | |
| Black % | 27.1 | 31.9 | 39.8 | 22.7 | 31.5 | |
| Hispanic % | 22.0 | 21.2 | 19.5 | 20.0 | 27.8 | |
| Hypertension | Yes % | 43.5 | 70.6* | 68.0* | 72.7* | 72.2* |
| ACE Inhibitor | Yes % | 12.2 | 29.2* | 25.8* | 32.1* | 31.5* |
| Alpha Blocker | Yes % | 3.8 | 6.2 | 7.8* | 4.6 | 5.6 |
| Beta Blocker | Yes % | 9.4 | 13.1 | 12.5 | 13.8 | 13 |
| Loop Diuretic | Yes % | 1.7 | 6.9* | 7.0* | 4.6* | 11.1* |
| Any Lipid Lowering | 16 | 18.6 | 21.9 | 15.6 | 16.7 | |
| Medication | Yes % | |||||
| Statin Medication | Yes% | 14.7 | 17.8 | 20.3 | 14.6 | 18.5 |
| Urine: albuminuria | 91.2 | 72.7* | 72.4* | 72.5* | 73.6* | |
| Normal % | ||||||
| Microalbuminuria % | 7.6 | 20.4 | 22.1 | 19.3 | 18.9 | |
| Macroalbuminuria % | 1.2 | 6.9 | 5.5 | 8.3 | 7.6 | |
| Smoking Status | 90.4 | 90.2 | 83.6* | 90 | 88.9 | |
| Never % | ||||||
| Former % | 7.3 | 7.4 | 11.7 | 5.5 | 9.3 | |
| Current % | 1.8 | 1.9 | 3.9 | 4.6 | 1.9 | |
| Diabetes | 74.5 | 57.9* | 60.9* | 54.6* | 57.4* | |
| Normal % | ||||||
| Impaired Fasting Glycemia % | 13.9 | 13.4 | 14.8 | 14.6 | 7.4 | |
| Untreated Diabetes % | 2.5 | 5.1 | 4.7 | 4.6 | 7.4 | |
| Treated Diabetes % | 9.1 | 23.6 | 19.5 | 26.4 | 27.8 | |
| EPA (mass%) | 0.76 (0.75, 0.77) | 0.69 (0.64, 0.74)* | 0.68 (0.61, 0.76)* | 0.69 (0.61, 0.76) | 0.71 (0.60, 0.84) | |
| DHA (mass%) | 3.75 (3.71, 3.78) | 3.50 (3.35, 3.66)* | 3.45 (3.21, 3.70)* | 3.44 (3.21, 3.69)* | 3.76 (3.39, 4.17) | |
| EPA+DHA (mass%) | 4.58 (4.54, 4.63) | 4.25 (4.06, 4.45)* | 4.18 (3.89, 4.5)* | 4.19 (3.9, 4.5)* | 4.54 (4.08, 5.05) | |
Note:
No HFa : free from heart failure
HFunk : heart failure with ejection fraction unmeasured
An * indicates a statistically significant (p<0.05) difference between the category and those in the No HF group