BIOCHEMISTRY, NEUROBIOLOGY.
The authors note the following for these three articles, “Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress,” by Tory M. Hagen, Jiankang Liu, Jens Lykkesfeldt, Carol M. Wehr, Russell T. Ingersoll, Vladimir Vinarsky, James C. Bartholomew, and Bruce N. Ames, which appeared in number 4, February 19, 2002, of Proc. Natl. Acad. Sci. USA (99, 1870–1875); “Age-associated mitochondrial oxidative decay: Improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L-carnitine and/or R-α-lipoic acid,” by Jiankang Liu, David W. Killilea, and Bruce N. Ames, which appeared in number 4, February 19, 2002, of Proc. Natl. Acad. Sci. USA (99, 1876–1881); and “Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: Partial reversal by feeding acetyl-L-carnitine and/or R-α-lipoic acid,” by Jiankang Liu, Elizabeth Head, Afshin M. Gharib, Wenjun Yuan, Russell T. Ingersoll, Tory M. Hagen, Carl W. Cotman, and Bruce N. Ames, which appeared in number 4, February 19, 2002, of Proc. Natl. Acad. Sci. USA (99, 2356–2361). B.N.A. is a founder of Juvenon and chair of its Scientific Advisory Board. T.M.H. is a founder of Juvenon and member of its Scientific Advisory Board. J. Liu has been a consultant to Juvenon. Juvenon is a company founded to study in humans the effects of biochemicals that reverse the mitochondrial decay of aging in rats.