Table 3.
Associations of Conjunctival Hemodynamic Biomarkers With POAG Versus NC as Reference
| Unadjusted Model | Adjusted Model* | |||
|---|---|---|---|---|
| Hemodynamic Biomarker | β (LCL, UCL) | Adjusted P Value† | β (LCL, UCL) | Adjusted P Value† |
| D (µm) | 1.48 (−0.124, 3.09) | 0.09 | 1.63 (−0.47, 3.73) | 0.16 |
| V (mm/s) | −0.05 (−0.09, −0.10) | 0.03 | −0.07 (−0.13, −0.01) | 0.03 |
| Q (pl/s) | −4.88 (−33.4, 23.6) | 0.73 | −12.9 (−51.6, 25.8) | 0.51 |
| WSR (s−1) | −31.3 (−53.0, −9.49) | 0.02 | −40.6 (−69.3, −11.8) | 0.02 |
| WSS (dyne/cm2) | −0.10 (−0.17, −0.04) | 0.005 | −0.12 (−0.21, −0.04) | 0.02 |
β, estimated slope; D, vessel diameter; LCL, lower 95% confidence limit; Q, blood flow; UCL, upper 95% confidence limit; V, cross sectional velocity.
Adjusted models included sex, race, age, MAP, HR, HCT, IOP as fixed effects.
P values were derived from linear mixed models and adjusted for multiple comparisons using Benjamini-Hochberg procedure.