3. SI of the Six Tumor Lines Tested with Thionaphthoquinones 7a and 7e and the Control.
|
selective
index (SI) per cell type
|
||||||
|---|---|---|---|---|---|---|
|
compound
|
oral cancer
|
colon cancer
|
hepatocellular carcinoma
|
melanoma
|
||
| SCC-9 | SCC-25 | SCC-4 | HCT-116 | HepG2 | B16-F10 | |
| 7a | 2.2 | 2.0 | 5.4 | 2.7 | 2.1 | 1.4 |
| 7e | 2.4 | 8.5 | 1.9 | 9.1 | 3.4 | 7.5 |
| carboplatin | 2.4 | 3.3 | 4.6 | 2.5 | 7.1 | 5.5 |