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. Author manuscript; available in PMC: 2025 Sep 19.
Published in final edited form as: Brain Res. 2025 Aug 7;1865:149874. doi: 10.1016/j.brainres.2025.149874

Table 4. Effects of 2-week finasteride without restraint on behavioral outcomes.

Mean ± S.E.M. for % time in the open arm on the elevated plus maze (left) and % time immobile on the forced swim test (right) after 2-week administration of finasteride (FIN) or vehicle (VEH) without restraint to the indicated groups of wild-type mice. Left, sex and age of experimental animals, Top, group designations. Pub, pubertal. Each row represents a different comparison within the behavioral sub-group. No comparisons were significantly different (7–10 mice/group).

Elevated plus maze Forced swim test
Sex VEH FIN P value VEH FIN P value
Female pub 36.1 ± 2.4 34.3 ± 1.4 0.53 57.2 ± 3.7 54.5 ± 1.8 0.58
Male pub 35.7 ± 2.6 36.5 ± 2.1 0.82 60.3 ± 4.7 66.9 ± 2.3 0.25
Female adult 31.0 ± 2.9 36.4 ± 2.4 0.18 59.2 ± 4.1 55.3 ± 2.4 0.44