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. 2025 Aug 13;5(5):oeaf098. doi: 10.1093/ehjopen/oeaf098

Table 2.

Non-invasive auricular acupressure and changes in blood pressure and heart rate

Study (author/year/design) Subjects/age Laterality/location of stimulation Duration of stimulation Changes in BP (mmHg) and HR (b.p.m.) before and after stimulations
Barker et al., 200621: sham controlled The 38 elderly with hip fracture: male 13.2%: 86 ± 4.8 (control, n = 20) vs. 87 ± 4.0 (active, n = 18) years 1 acupoint without affect haemodynamics (control)
3 selected acupoints (active)
1 min In the sham stimulation group, the values in SBP/DBP/HR before and after procedure were 125 ± 7.4/78 ± 7.7/92 ± 12 and 126 ± 20/81 ± 13/90 ± 8.0, respectively.
In the active stimulation group, the mean changes in SBP/DBP/HR before and after procedure were 125 ± 12/74 ± 9.4/95 ± 8.3 and 120 ± 19/73 ± 13/73 ± 9.4, respectively.
Yeh et al., 201522: randomized, controlled 123 hypertensives: male 48.8%: 61 ± 7.7 (control, n = 60) vs. 60 ± 7.4 (active, n = 63) years Routine care (control)
6 selected acupoints (active)
2 min (3 times/day for 10 weeks) In the control group, the values in SBP/DBP/HR before and after procedure were 125 ± 14/78 ± 4.2/69 ± 12 and 122 ± 14/77 ± 3.6/70 ± 13, respectively.
In the active acupressure group, the values in SBP/DBP/HR before and after procedure were 127 ± 14/78 ± 5.3/64 ± 11 and 124 ± 13/76 ± 5.2/70 ± 11, respectively.
Kuo et al., 201623: randomized, controlled 76 females with postpartum: male 0%: 33 ± 4.3 (control, n = 37) vs. 33 ± 3.6 (active, n = 39) years Routine care (control)
1 selected acupoints (active)
3 min (2 times/day for 4 days) In the control group, the values in SBP/DBP/HR before and after procedure were 113 ± 16/72 ± 9.1/84 ± 12 and 119 ± 13/79 ± 9.6/86 ± 9.1, respectively.
In the active acupressure group, the values in SBP/DBP/HR before and after procedure were 108 ± 16/70 ± 9.5/84 ± 12 and 113 ± 16/76 ± 12/77 ± 9.0, respectively.
Park et al., 202324: sham controlled The 46 hypertensives: male 39.1%: 84 ± 5.7 (control, n = 22) vs. 82 ± 5.6 (active, n = 24) 5 selected acupoints not related with haemodynamics (control)
5 selected acupoints related with haemodynamics (active)
N/A
(5 times/day for 8 weeks)
In the control group, the values in SBP/DBP/HR before and after procedure
were 139 ± 3.2/79 ± 1.4/72 ± 2.4 and 133 ± 2.7/73 ± 2.2/73 ± 2.0, respectively.
In the active acupressure group, the values in SBP/DBP/HR before and after procedure
were 146 ± 3.1/82 ± 1.3/74 ± 2.3 and 128 ± 2.6/77 ± 2.1/73 ± 1.9, respectively.
Kim and Park, 202325: placebo controlled The 46 hypertensives: male 0%: 70 ± 4.8 (control, n = 23) vs. 71 ± 5.3 (active, n = 23) No acupressure (control)
5 selected acupoints (active)
N/A (8 weeks) In the control group, the values in SBP/DBP/HR before and after procedure were 151 ± 8.3/83 ± 5.8/77 ± 4.0 and 150 ± 9.3/86 ± 8.1/77 ± 3.8, respectively.
In the active stimulation, the values in SBP/DBP/HR before and after procedure were 147 ± 6.8/83 ± 5.6/79 ± 6.8 and 141 ± 5.3/79 ± 4.5/74 ± 5.6, respectively.
Sajadi et al., 202326: sham controlled 94 males undergoing non-emergency coronary angiography: male 100%: 52 ± 12 (control, n = 47) vs. 55 ± 12 (active, n = 47) years 4 selected acupoints not-related with anxiety and endocrine (control)
4 selected acupoints related with anxiety and endocrine (active)
Each point for 1 min (60 min before angiography) In the sham group, the values in SBP/DBP/HR before and after procedure were 134 ± 1.3/90 ± 2.0/81 ± 1.9 and 133 ± 1.2/90 ± 1.9/81 ± 1.7, respectively.
In the active acupressure group, the values in SBP/DBP/HR before and after procedure were 135 ± 1.2/89 ± 1.6/85 ± 1.3 and 132 ± 1.1/88 ± 1.6/81 ± 1.2, respectively.
Keshtkar et al., 202410: randomized controlled 80 females with gestational hypertension: male 0%: 28 ± 5.0 (control, n = 40) vs. 27 ± 4.9 (active, n = 40) years Routine care (control)
Selected acupoints (active)
6 times a day for at least 1 min (twice a week for 1 month) In the control group, the values in SBP/DBP before and after procedure were 142 ± 4.6/88 ± 6.2/and 136 ± 5.0/84 ± 4.9, respectively.
In the active acupressure group, the values in SBP/DBP before and after procedure were 143 ± 4.4/88 ± 6.2 and 131 ± 4.0/80 ± 1.2, respectively.

BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure.