Table 1:

Annex A - Search strategy for each database

Database	Date conducted	Search strategy
PubMed	May 4, 2024	“Icosapent ethyl” [tiab] OR vascepa[tiab] OR amr101[tiab] OR amr-101[tiab] OR “eicosapentaenoic acid ethyl ester”[Supplementary Concept] OR “ethyl eicosapentaenoate”[tiab] OR “ethyl icosapentaenoate”[tiab] OR “ethyl eicosapentaenoic acid”[tiab] OR ethyl-EPA[tiab] OR “icosapent ethyl”[tiab] OR “ethyl eicosapentaenoic acid”[tiab] OR Epadel[tiab] OR icosapent[tiab]
Web of Science	May 4, 2024	TS=(“Icosapent ethyl” OR vascepa OR amr101 OR amr-101 OR “eicosapentaenoic acid ethyl ester” OR “ethyl eicosapentaenoate”)
NHS Economic Evaluation Database (NHS EED) and the health technology assessment		((icosapent ethyl):TI OR (vascepa ):TI OR (amr101):TI) and ((Systematic review:ZDT and Bibliographic:ZPS) OR (Systematic review:ZDT and Abstract:ZPS) OR (Cochrane review:ZDT) OR (Cochrane related review record:ZDT) OR (Economic evaluation:ZDT and Bibliographic:ZPS) OR (Economic evaluation:ZDT and Abstract:ZPS) OR Project record:ZDT OR Full publication record:ZDT) IN DARE, NHSEED
Embase	May 4, 2024	‘icosapentaenoic acid ethyl ester’/exp OR ‘icosapentaenoic acid ethyl ester’ OR vascepa:ti,ab,kw OR amr101:ti,ab,kw OR amr-101:ti,ab,kw
Scopus	May 4, 2024	TITLE-ABS-KEY (“’icosapentaenoic acid ethyl ester” OR vascepa OR amr101 OR amr-101 OR “Icosapent ethyl”)