Table 2.
Summary of outcome regarding the different surgical techniques
| Outcome parameters | OAN | ORN | LDN | RDN | P-value |
|---|---|---|---|---|---|
| Outcome reported by transplant centers | |||||
| Skin-to-skin time (min) median (Q25–Q75) | 134 (92–178) | 125 (99–175) | 185 (153–228) | 123 (105–155) | < 0.001 |
| Reoperations, n (%) | 0 | 0 | 10 (1.8) | 3 (1.6) | 0.382 |
| Conversion rate, n (%) | --- | --- | 12 (2.8) | 2 (1.3) | n.a. |
| Overall complication rate, n (%) | 6 (17.1) | 19 (13.1) | 79 (14.3) | 19 (9.8) | 0.369 |
| Graft injury, n (%) | n = 3 (4.3) | n = 10 (3.5) | n = 22 (2.0) | n = 11 (2.9) | 0.230 |
| Discharge from hospital (d) median (Q25–Q75) | 7 (6–8) | 6 (6–8) | 6 (5–7) | 4 (4–5) | < 0.001 |
| Readmission, n (%) | 1 (2.9) | 6 (4.1) | 14 (2.5) | 5 (2.6) | 0.684 |
| Self-reported outcome 8–14 wks after donation (POST) | |||||
| Complication rate, n (%) | 3 (15.0) | 12 (12.2) | 53 (12.3) | 18 (13.0) | 0.958 |
| Return to work (wks), mean ± SD | 7.0 ± 3.4 | 7.4 ± 4.2 | 6.6 ± 3.5 | 6.5 ± 3.5 | 0.289 |
| > 50% fit, n (%) | 14 (70.0) | 79 (81.4) | 357 (83.8) | 118 (84.9) | 0.360 |
| No limitations in everyday life, n (%) | 10 (47.6) | 51 (52.0) | 230 (53.2) | 80 (57.1) | 0.767 |
| PCS SF-12, mean ± SD | 46.2 ± 10.4 | 48.5 ± 7.8 | 48.1 ± 8.4 | 48.6 ± 8.3 | 0.636 |
| MCS SF-12, median (Q25–Q75) | 57.1 (51.0–60.3) | 56.2 (51.6–59.5) | 57.5 (53.0;59.4) | 57.8 (52.0–59.5) | 0.898 |
| Willing to donate again (yes in any case or rather yes), n (%) | 20 (100) | 96 (98.0) | 413 (95.8) | 135 (96.4) | 0.836 |
LDN, laparoscopic donor nephrectomy; MCS, mental component summary score; n.a., not applicable; n.s., not significant; OAN, open abdominal nephrectomy; ORN, open retroperitoneal nephrectomy; PCS, physical component summary score; RDN, retroperitoneoscopic donor nephrectomy. SF-12, Short Form–12 questionnaire.