Table 3.

Comparison of inflammatory and metabolic indices in the EO-PE, LO-PE, and control groups

	EO-PE n = 170 (47.7%)	Control n = 155 (52.3%)	p value	Adjusted p value*	LO-PE n = 150 (50%)	Control n = 150 (50%)	p value	Adjusted p value*	EO-PE n = 170 (53.1%)	LO-PE n = 150 (46.9%)	p value
Uric acid/Albumin ratio	0.1682 (0.1047)	0.0997 (0.0293)	< 0.001a	< 0.001	0.1608 (0.0666)	0.0973 (0.0339)	< 0.001a	< 0.001	0.1682 (0.1047)	0.1608 (0.0666)	0.730a
Fibrinogen/Uric acid ratio	84.37 (51.43)	125.56 (45.93)	< 0.001a	0.002	93.76 (37.29)	127.22 (51.81)	< 0.001a	< 0.001	84.37 (51.43)	93.76 (37.29)	0.186a
Uric acid/Creatinine ratio	8.79 (3.54)	7.69 (2.84)	< 0.001a	0.012	9.11 (3.32)	7.06 (3.46)	< 0.001a	< 0.001	8.79 (3.54)	9.11 (3.32)	0.316a
Creatinin/Body weight ratio	0.0083 (0.0044)	0.0077 (0.0025)	0.092a	-	0.0078 (0.0031)	0.0078 (0.0034)	0.593a	-	0.0083 (0.0044)	0.0078 (0.0031)	0.467a
AST/PLT ratio	0.0849 (0.0765)	0.0625 (0.0329)	< 0.001a	0.015	0.0812 (0.0655)	0.0628 (0.0389)	< 0.001a	< 0.001	0.0849 (0.0765)	0.0812 (0.0655)	0.335a
AST/ALT ratio	1.43 (0.77)	1.5 (0.75)	0.098a	-	1.63 (0.67)	1.56 (0.67)	0.106a	-	1.43 (0.77)	1.63 (0.67)	0.006a
FIB 4	0.7228 (0.5648)	0.5757 (0.3195)	< 0.001a	0.021	0.7047 (0.5704)	0.5409 (0.3211)	< 0.001a	< 0.001	0.7228 (0.5648)	0.7047 (0.5704)	0.754a
FIB 5	43.27 (6.5)	45.32 (8.09)	0.009a	0.017	44.47 (7.04)	45.26 (5.83)	0.526a	-	43.27 (6.5)	44.47 (7.04)	0.121a

Data are expressed as n (%) or median (IQR) where appropriate. A p value of < 0.05 indicates a significant difference and statistically significant p-values are in bold. EO-PE Early onset preeclampsia; LO-PE Late onset preeclampsia; AST Aspartate aminotransferase; ALT Alanine aminotransferase; PLT Platelet count; FIB 4 Fibrosis 4 index; FIB 5 Fibrosis 5 index, ^a: Mann-Whitney U test

* Adjusted p-values were calculated using logistic regression models controlling for maternal age and body mass index (BMI)