Table 4.
Association of inflammatory and metabolic indices with EO-PE and LO-PE status
| LR+ | LR- | Cut-off * | Sensitivity | Specificity | AUC | %95 CI | P-value | |
|---|---|---|---|---|---|---|---|---|
| EO-PE group | ||||||||
| Uric acid/Albumin ratio | 3.77 | 0.28 | > 0.1170 | 77.6% | 79.4% | 0.831 | 0.79–0.88 | < 0.001 |
| Fibrinogen/Uric acid ratio | 2.29 | 0.44 | < 111.85 | 69.5% | 69.7% | 0.752 | 0.69–0.81 | < 0.001 |
| Uric acid/Creatinine ratio | 1.69 | 0.61 | > 8.21 | 61.2% | 63.9% | 0.663 | 0.60–0.72 | < 0.001 |
| AST/PLT ratio | 1.62 | 0.63 | > 0.0694 | 60.6% | 62.6% | 0.686 | 0.63–0.74 | < 0.001 |
| FIB 4 | 1.84 | 0.59 | > 0.6297 | 60.6% | 67.1% | 0.669 | 0.61–0.73 | < 0.001 |
| FIB 5 | 1.35 | 0.76 | < 44.21 | 54.9% | 59.4% | 0.603 | 0.53–0.68 | 0.009 |
| LO-PE group | ||||||||
| Uric acid/Albumin ratio | 4.46 | 0.20 | > 0.1222 | 83.3% | 81.3% | 0.888 | 0.85–0.93 | < 0.001 |
| Fibrinogen/Uric acid ratio | 2.5 | 0.42 | < 111.33 | 70% | 72% | 0.775 | 0.72–0.83 | < 0.001 |
| Uric acid/Creatinine ratio | 2.07 | 0.51 | > 8.51 | 64.7% | 68.7% | 0.716 | 0.66–0.77 | < 0.001 |
| AST/PLT ratio | 1.55 | 0.65 | > 0.0725 | 60% | 61.3% | 0.646 | 0.58–0.71 | < 0.001 |
| FIB 4 | 1.53 | 0.65 | > 0.6045 | 61.3% | 60% | 0.641 | 0.58–0.71 | < 0.001 |
* Cut-off values were found according to Youden index. LR+ Positive likelihood ratio; LR- Negative likelihood ratio; AUC Area under the curve; CI Confidence interval; AST Aspartate aminotransferase; PLT Platelet count; FIB 4 Fibrosis 4 index; FIB 5 Fibrosis 5 index