Table 6.
The predictive performance of inflammatory and metabolic indices for prediction of CANO in EO-PE and LO-PE groups
| LR+ | LR- | Cut-off * | Sensitivity | Specificity | AUC | %95 CI | P-value | |
|---|---|---|---|---|---|---|---|---|
| EO-PE group | ||||||||
| Uric acid/Albumin ratio | 3.4 | 0.28 | > 0.1388 | 68% | 80% | 0.831 | 0.70–0.82 | < 0.001 |
| Fibrinogen/Uric acid ratio | 2.31 | 0.44 | < 104.09 | 68.2% | 70.5% | 0.733 | 0.67–0.80 | < 0.001 |
| Uric acid/Creatinine ratio | 1.72 | 0.62 | > 8.55 | 59.2% | 65.5% | 0.627 | 0.56–0.69 | < 0.001 |
| Creatinine/Body weight ratio | 2.05 | 0.54 | > 0.0082 | 62.4% | 69.5% | 0.651 | 0.59–0.71 | < 0.001 |
| AST/PLT ratio | 1.71 | 0.6 | > 0.0728 | 61.6% | 64% | 0.686 | 0.62–0.74 | < 0.001 |
| AST/ALT ratio | - | - | - | - | - | - | - | 0.072 |
| FIB 4 | 1.5 | 0.68 | > 0.6425 | 58.4% | 61% | 0.669 | 0.55–0.68 | < 0.001 |
| FIB 5 | 1.76 | 0.65 | < 44.35 | 55.3% | 68.6% | 0.629 | 0.56–0.70 | 0.001 |
| LO-PE group | ||||||||
| Uric acid/Albumin ratio | 1.50 | 0.65 | > 0.1289 | 62.1% | 58.7% | 0.606 | 0.52–0.69 | 0.012 |
| Fibrinogen/Uric acid ratio | 2.5 | 0.42 | < 111.33 | 70% | 72% | 0.775 | 0.72–0.83 | < 0.001 |
| Uric acid/Creatinine ratio | 1.30 | 0.77 | > 8.57 | 56.9% | 56.2% | 0.586 | 0.50–0.67 | 0.042 |
| Creatinine/Body weight ratio | - | - | - | - | - | - | - | 0.584 |
| AST/PLT ratio | - | - | - | - | - | - | - | 0.061 |
| AST/ALT ratio | - | - | - | - | - | - | - | 0.935 |
| FIB 4 | - | - | - | - | - | - | - | 0.077 |
| FIB 5 | - | - | - | - | - | - | - | 0.225 |
* Cut-off values were found according to Youden index. LR+ Positive likelihood ratio; LR- Negative likelihood ratio; AUC Area under the curve; CI Confidence interval; AST Aspartate aminotransferase; ALT Alanine aminotransferase; PLT Platelet count; FIB 4 Fibrosis 4 index; FIB 5 Fibrosis 5 index